Chen-Hua Yan Selected Research

Residual Neoplasm

1/2022	Monitoring of post-transplant MLL-PTD as minimal residual disease can predict relapse after allogeneic HSCT in patients with acute myeloid leukemia and myelodysplastic syndrome.
1/2022	Preemptive Interferon-α Therapy Could Protect Against Relapse and Improve Survival of Acute Myeloid Leukemia Patients After Allogeneic Hematopoietic Stem Cell Transplantation: Long-Term Results of Two Registry Studies.
12/2021	A risk score system for stratifying the risk of relapse in B cell acute lymphocytic leukemia patients after allogenic stem cell transplantation.
5/2021	Minimal residual disease monitoring and preemptive immunotherapies for frequent 11q23 rearranged acute leukemia after allogeneic hematopoietic stem cell transplantation.
3/2021	Wilms' tumor gene 1 is an independent prognostic factor for pediatric acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation.
1/2021	Preemptive Immunotherapy for Minimal Residual Disease in Patients With t(8;21) Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation.
1/2021	Efficacy of Haploidentical Hematopoietic Stem Cell Transplantation Compared With Chemotherapy as Postremission Treatment of Children With Intermediate-risk Acute Myeloid Leukemia in First Complete Remission.
1/2021	Dynamic immune profiling identifies the stronger graft-versus-leukemia (GVL) effects with haploidentical allografts compared to HLA-matched stem cell transplantation.
1/2021	Chimeric Antigens Receptor T Cell Therapy Improve the Prognosis of Pediatric Acute Lymphoblastic Leukemia With Persistent/Recurrent Minimal Residual Disease in First Complete Remission.
6/2020	Allogeneic hematopoietic stem cell transplantation can improve the prognosis of high-risk pediatric t(8;21) acute myeloid leukemia in first remission based on MRD-guided treatment.

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Chen-Hua Yan Research Topics

Disease

31	Residual Neoplasm 01/2022 - 10/2013
30	Leukemia 05/2022 - 04/2012
21	Graft vs Host Disease (Graft-Versus-Host Disease) 05/2022 - 11/2012
15	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022 - 01/2016
14	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/2021 - 09/2014
9	Hematologic Neoplasms (Hematological Malignancy) 11/2021 - 06/2011
9	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2021 - 11/2015
7	Infections 01/2022 - 01/2016
6	Aplastic Anemia (Anemia, Hypoplastic) 01/2022 - 01/2019
6	Bronchiolitis Obliterans Syndrome 01/2022 - 10/2013
5	Philadelphia Chromosome 11/2021 - 04/2015
3	Hematologic Diseases (Blood Diseases) 11/2020 - 01/2019
2	Pneumonia (Pneumonitis) 10/2021 - 11/2020
2	Disease Progression 01/2021 - 01/2019
2	Thrombocytopenia (Thrombopenia) 01/2019 - 01/2018
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2016 - 01/2016
1	Hemorrhage 01/2022
1	Cytomegalovirus Infections (Inclusion Disease) 01/2022
1	Thrombotic Microangiopathies 01/2022
1	Viremia 06/2021
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 06/2021
1	Myeloid Sarcoma (Chloroma) 03/2021
1	Acute Cholecystitis 01/2021
1	Neoplasms (Cancer) 12/2020
1	Encephalitis (Encephalitis, Rasmussen) 11/2020
1	Ischemic Stroke 11/2020
1	Gastroenteritis 11/2020
1	Retinitis 11/2020
1	Stroke (Strokes) 11/2020
1	Venous Thromboembolism 10/2020
1	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 08/2020
1	Pancreatitis 01/2020
1	Tuberculosis (Tuberculoses) 01/2020
1	Cytomegalovirus Retinitis 01/2020
1	Cardiotoxicity 10/2019
1	Cytopenia 08/2019
1	Hepatitis 01/2019
1	Acute Promyelocytic Leukemia 01/2019
1	Mucositis 11/2018
1	Sepsis (Septicemia) 11/2018
1	Hemorrhagic Cystitis 07/2018
1	Mycoses (Diseases, Fungus) 07/2017
1	Melanoma (Melanoma, Malignant) 08/2016
1	Thrombosis (Thrombus) 08/2016
1	Blast Crisis (Blast Phase) 01/2016
1	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 12/2015
1	Heart Failure 09/2013

Drug/Important Bio-Agent (IBA)

7	InterferonsIBA 01/2022 - 11/2015
7	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022 - 08/2014
4	AntigensIBA 11/2021 - 08/2014
3	Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA 01/2020 - 08/2017
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2020 - 03/2016
3	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2018 - 01/2016
2	Chimeric Antigen ReceptorsIBA 11/2021 - 12/2020
2	AntibodiesIBA 11/2020 - 01/2019
2	Basiliximab FDA Link 01/2020 - 01/2020
2	SteroidsIBA 01/2020 - 01/2020
2	Immunoglobulin G (IgG)IBA 01/2019 - 01/2019
1	Indicators and Reagents (Reagents)IBA 01/2022
1	BilirubinIBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 06/2021
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2021
1	CytokinesIBA 01/2021
1	Therapeutic UsesIBA 01/2020
1	HLA-B Antigens (HLA-B)IBA 01/2019
1	Thrombopoietin (c-mpl Ligand)IBA 01/2019
1	HLA-A Antigens (HLA-A)IBA 01/2019
1	Biological ProductsIBA 01/2019
1	Tyrosine Kinase InhibitorsIBA 01/2019
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2019
1	Carbapenems (Carbapenem Antibiotics)IBA 11/2018
1	Interferon-alpha (Interferon Alfa)IBA 11/2018
1	Acetylcysteine (Siran)FDA LinkGeneric 01/2018
1	C-Reactive ProteinIBA 02/2017
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2017
1	Interleukin-2 (IL2)IBA 01/2016
1	Biomarkers (Surrogate Marker)IBA 01/2016
1	Methotrexate (Mexate)FDA LinkGeneric 07/2015
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 07/2015

Therapy/Procedure

71	Hematopoietic Stem Cell Transplantation 05/2022 - 06/2011
25	Transplantation 01/2022 - 04/2012
18	Stem Cell Transplantation 01/2022 - 06/2015
16	Therapeutics 01/2022 - 09/2014
10	Drug Therapy (Chemotherapy) 01/2021 - 10/2013
5	Haploidentical Transplantation 01/2021 - 01/2016
3	Immunotherapy 05/2021 - 08/2016
3	Induction Chemotherapy 01/2021 - 01/2016
2	Consolidation Chemotherapy 03/2019 - 01/2016
2	Cell Transplantation 01/2018 - 01/2016
1	Homologous Transplantation 01/2022
1	Plasma Exchange 01/2022
1	Total Parenteral Nutrition 01/2021
1	Platelet Transfusion (Blood Platelet Transfusions) 11/2020
1	Donor Selection 11/2020
1	Aftercare (After-Treatment) 11/2018
1	Catheters 08/2016